Medicinal Plants and Neuroprotection
Researchers in this area investigate how plant-derived compounds — particularly those found in Ayurvedic herbs like Centella asiatica and Bacopa monnieri — can protect neurons, reduce oxidative stress, and improve cognitive function. The active molecules at the center of this work, including triterpenoids such as asiatic acid, appear to modulate pathways implicated in neurodegenerative diseases like Alzheimer's, making them candidates for treatments that carry fewer side effects than many synthetic drugs. A key challenge is translating promising laboratory and traditional-use evidence into rigorous clinical proof: questions remain about optimal dosing, bioavailability, and which molecular mechanisms actually drive the observed effects in humans. Active directions include isolating and standardizing the specific phytochemicals responsible for neuroprotection, and exploring how these compounds might complement or enhance conventional neurological therapies.
- Works
- 32,877
- Total citations
- 266,942
- Keywords
- Centella asiaticaBacopa monnieriAsiatic acidNeuroprotectiveCognitive enhancementAntioxidant activity
Top papers in Medicinal Plants and Neuroprotection
Ordered by total citation count.
- Essential oils: their antibacterial properties and potential applications in foods—a review↗ 10,373
- A simple method for organotypic cultures of nervous tissue↗ 3,176OA
- A review on plants extract mediated synthesis of silver nanoparticles for antimicrobial applications: A green expertise↗ 2,935OA
- Antimicrobial activity of metals: mechanisms, molecular targets and applications↗ 2,711
- Curcumin: A Review of Its Effects on Human Health↗ 2,625OA
- Acetylcholinesterase Inhibitors: Pharmacology and Toxicology↗ 2,571OA
- CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis↗ 2,104OA
- Glutamate: A Neurotransmitter in Mammalian Brain↗ 1,990
- Glutamate Induces Calcium Waves in Cultured Astrocytes: Long-Range Glial Signaling↗ 1,851
- Microtitre plate-based antibacterial assay incorporating resazurin as an indicator of cell growth, and its application in the in vitro antibacterial screening of phytochemicals↗ 1,827OA
- TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model↗ 1,814OA
- Antimicrobial Activity of Some Essential Oils—Present Status and Future Perspectives↗ 1,543OA
Active researchers
Top authors in this area, ranked by h-index.