Medicinal Plants and Neuroprotection
Researchers investigating medicinal plants and neuroprotection examine how compounds derived from botanical sources—particularly herbs long used in Ayurvedic tradition such as Centella asiatica and Bacopa monnieri—can protect neurons, reduce oxidative stress, and support cognitive function. The active constituents at the center of this work, including triterpenoids like asiatic acid, appear to modulate cellular pathways relevant to conditions such as Alzheimer's disease, making them candidates for treatments where conventional options remain limited. A central challenge is translating promising laboratory findings into rigorous clinical evidence, since most mechanistic studies rely on cell cultures or animal models that do not always predict human outcomes. Active directions include characterizing the precise molecular targets of these compounds, establishing safe and effective dosing regimens, and determining how traditional preparations compare to isolated bioactive fractions.
- Works
- 32,511
- Total citations
- 263,956
- Keywords
- Centella asiaticaBacopa monnieriAsiatic acidNeuroprotectiveCognitive enhancementAntioxidant activity
Top papers in Medicinal Plants and Neuroprotection
Ordered by total citation count.
- Essential oils: their antibacterial properties and potential applications in foods—a review↗ 10,296
- A simple method for organotypic cultures of nervous tissue↗ 3,164OA
- A review on plants extract mediated synthesis of silver nanoparticles for antimicrobial applications: A green expertise↗ 2,859OA
- Antimicrobial activity of metals: mechanisms, molecular targets and applications↗ 2,679
- Curcumin: A Review of Its Effects on Human Health↗ 2,562OA
- Acetylcholinesterase Inhibitors: Pharmacology and Toxicology↗ 2,539OA
- CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis↗ 2,077OA
- Glutamate: A Neurotransmitter in Mammalian Brain↗ 1,989
- Glutamate Induces Calcium Waves in Cultured Astrocytes: Long-Range Glial Signaling↗ 1,847
- Microtitre plate-based antibacterial assay incorporating resazurin as an indicator of cell growth, and its application in the in vitro antibacterial screening of phytochemicals↗ 1,803OA
- TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model↗ 1,795OA
- Antimicrobial Activity of Some Essential Oils—Present Status and Future Perspectives↗ 1,518OA
Active researchers
Top authors in this area, ranked by h-index.