Cardiovascular and exercise physiology

Cardiovascular and exercise physiology examines how the heart, lungs, and skeletal muscles coordinate to meet the body's demand for oxygen during physical activity, and how structured exercise interventions—from aerobic training to high-intensity interval protocols—reshape these systems over time. Researchers in this area are particularly interested in populations where that coordination breaks down, such as patients with heart failure, whose reduced oxygen uptake and impaired cardiac output sharply limit daily function and survival. A growing line of work explores whether techniques like blood flow restriction training can produce meaningful gains in cardiorespiratory fitness at lower absolute workloads, opening options for people who cannot tolerate conventional exercise intensities. Central open questions include how to reliably predict and improve exercise capacity across disease states, and what molecular changes in skeletal muscle underlie the adaptations—or the failure to adapt—that distinguish responders from non-responders to training.

Works

89,980

Total citations

1,376,791

Keywords

Exercise CapacityCardiorespiratory FitnessHigh-Intensity Interval TrainingAerobic ExerciseHeart FailureBlood Flow Restriction