Lung Cancer Diagnosis and Treatment
Lung cancer kills more people worldwide than any other cancer, largely because most cases are caught only after the disease has spread beyond the lung. Clinicians and researchers work to change that through low-dose CT screening programs capable of detecting small nodules years before symptoms appear, while imaging tools like positron emission tomography help determine how far a tumor has advanced—information that drives every subsequent treatment decision. Once staged, patients may receive surgery, chemotherapy, radiotherapy, or newer targeted approaches such as stereotactic body radiation therapy, often in combination as adjuvant strategies aimed at eliminating residual disease. Active questions center on which screening populations benefit most, how to distinguish harmless nodules from early malignancies without unnecessary intervention, and how to sequence or personalize treatments for the genetically diverse subtypes of non-small cell lung cancer.
- Works
- 131,150
- Total citations
- 1,597,655
- Keywords
- Lung CancerCT ScreeningRadiotherapyChemotherapyTumor StagingAdjuvant Therapy
Top papers in Lung Cancer Diagnosis and Treatment
Ordered by total citation count.
- The European Organization for Research and Treatment of Cancer QLQ-C30: A Quality-of-Life Instrument for Use in International Clinical Trials in Oncology↗ 15,947
- Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib↗ 11,500
- Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening↗ 10,969OA
- Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer↗ 10,087OA
- Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer↗ 9,456OA
- Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma↗ 8,245OA
- Pembrolizumab plus Chemotherapy in Metastatic Non–Small-Cell Lung Cancer↗ 6,601OA
- Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial↗ 6,532
- Deep Convolutional Neural Networks for Computer-Aided Detection: CNN Architectures, Dataset Characteristics and Transfer Learning↗ 5,796OA
- Paclitaxel–Carboplatin Alone or with Bevacizumab for Non–Small-Cell Lung Cancer↗ 5,777OA
- Gefitinib or Chemotherapy for Non–Small-Cell Lung Cancer with Mutated EGFR↗ 5,570
- Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial↗ 5,526OA
Active researchers
Top authors in this area, ranked by h-index.