Health SciencesMedicinePulmonary and Respiratory Medicine

Lung Cancer Diagnosis and Treatment

Lung cancer kills more people worldwide than any other cancer, making accurate diagnosis and effective treatment among the most consequential problems in medicine. Clinicians and researchers work to detect tumors as early as possible — often through low-dose CT screening or positron emission tomography — and then stage them precisely to determine whether surgery, stereotactic body radiation therapy, chemotherapy, or some combination offers the best chance of survival. Open questions center on how to manage the vast number of small pulmonary nodules that screening programs inevitably uncover, most of which are benign, and on identifying which patients with early-stage disease will benefit from adjuvant therapy after their primary treatment. Advances in tumor biology and imaging are steadily refining these decisions, but the gap between what screening can detect and what treatment can reliably cure remains a defining challenge of the field.

Works
132,434
Total citations
1,610,592
Keywords
Lung CancerCT ScreeningRadiotherapyChemotherapyTumor StagingAdjuvant Therapy

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