Lung Cancer Diagnosis and Treatment
Lung cancer remains the leading cause of cancer death worldwide, largely because most cases are caught only after the disease has already spread, making early and accurate diagnosis a central challenge. Researchers work across imaging techniques such as low-dose CT screening and positron emission tomography to detect tumors at earlier stages, while refining how those tumors are classified and staged to guide treatment decisions. On the treatment side, surgery, chemotherapy, radiotherapy, and newer approaches like stereotactic body radiation therapy are often combined in carefully sequenced regimens, with ongoing investigation into which adjuvant therapies best reduce the risk of recurrence after initial treatment. Key open questions include how to distinguish truly dangerous pulmonary nodules from benign ones found incidentally during screening, and how to personalize treatment for the molecularly diverse subtypes of non-small cell lung cancer.
- Works
- 129,894
- Total citations
- 1,584,292
- Keywords
- Lung CancerCT ScreeningRadiotherapyChemotherapyTumor StagingAdjuvant Therapy
Top papers in Lung Cancer Diagnosis and Treatment
Ordered by total citation count.
- The European Organization for Research and Treatment of Cancer QLQ-C30: A Quality-of-Life Instrument for Use in International Clinical Trials in Oncology↗ 15,803
- Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib↗ 11,471
- Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening↗ 10,872OA
- Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer↗ 9,989OA
- Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer↗ 9,415OA
- Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma↗ 8,224OA
- Pembrolizumab plus Chemotherapy in Metastatic Non–Small-Cell Lung Cancer↗ 6,528OA
- Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial↗ 6,500
- Paclitaxel–Carboplatin Alone or with Bevacizumab for Non–Small-Cell Lung Cancer↗ 5,768OA
- Deep Convolutional Neural Networks for Computer-Aided Detection: CNN Architectures, Dataset Characteristics and Transfer Learning↗ 5,748OA
- Gefitinib or Chemotherapy for Non–Small-Cell Lung Cancer with Mutated EGFR↗ 5,557
- Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial↗ 5,513OA
Active researchers
Top authors in this area, ranked by h-index.