Health SciencesMedicineOphthalmology

Glaucoma and retinal disorders

Glaucoma is a progressive eye disease in which damage to the optic nerve—often driven by elevated intraocular pressure—leads to the irreversible loss of retinal ganglion cells and, over time, permanent vision loss affecting tens of millions of people worldwide. Researchers study how mechanical, vascular, and neurodegenerative processes interact to determine which patients progress from ocular hypertension to clinical disease, and tools like optical coherence tomography now allow clinicians to detect subtle structural changes in the retina and optic nerve before patients notice any symptoms. Central open questions include why some individuals with normal intraocular pressure still develop glaucoma, and how to identify early biomarkers that reliably predict visual field progression so that treatment can be tailored before significant nerve damage occurs.

Works
154,114
Total citations
2,026,516
Keywords
GlaucomaIntraocular PressureOptic NerveRetinal Ganglion CellsOcular HypertensionOptical Coherence Tomography

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