Genetic diversity and population structure
Population genetics examines how genetic variation is distributed within and among groups of organisms, and what forces — mutation, migration, natural selection, and random drift — shape that variation over time. Understanding the genetic structure of populations helps researchers trace evolutionary histories, identify distinct species or subspecies, and pinpoint the molecular signatures of adaptation to local environments. Tools like microsatellite markers and Bayesian statistical methods have made it possible to reconstruct past population dynamics with increasing precision, even from small or degraded samples. Active challenges include disentangling the effects of selection from demographic history, and developing robust criteria for species delimitation in groups where genetic and geographic boundaries don't align neatly.
- Works
- 269,651
- Total citations
- 2,551,810
- Keywords
- Population GeneticsGenetic StructurePopulation DynamicsMicrosatellite AnalysisBayesian InferenceGenetic Diversity
Top papers in Genetic diversity and population structure
Ordered by total citation count.
- The neighbor-joining method: a new method for reconstructing phylogenetic trees.↗ 60,363OA
- MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0↗ 47,788OA
- MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods↗ 40,263OA
- Inference of Population Structure Using Multilocus Genotype Data↗ 34,069OA
- RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies↗ 34,004OA
- MrBayes 3: Bayesian phylogenetic inference under mixed models↗ 29,257OA
- MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0↗ 28,806OA
- MrBayes 3.2: Efficient Bayesian Phylogenetic Inference and Model Choice Across a Large Model Space↗ 27,607OA
- MRBAYES: Bayesian inference of phylogenetic trees↗ 22,099OA
- Detecting the number of clusters of individuals using the software <scp>structure</scp>: a simulation study↗ 21,976OA
- MEGA11: Molecular Evolutionary Genetics Analysis Version 11↗ 21,374OA
- MODELTEST: testing the model of DNA substitution.↗ 20,075
Active researchers
Top authors in this area, ranked by h-index.