Life SciencesBiochemistry, Genetics and Molecular BiologyGenetics

Forensic and Genetic Research

Forensic and genetic research draws on ancient DNA extracted from archaeological remains to reconstruct how human populations moved, mixed, and diverged over tens of thousands of years. By examining markers in mitochondrial DNA, the Y chromosome, and across the full genome, researchers can trace lineages, identify episodes of migration and admixture, and build detailed pictures of population history that written records cannot reach. One central challenge is the degraded and fragmentary nature of ancient genetic material, which demands careful computational methods to distinguish true biological signals from contamination or chemical damage. Open questions include the precise timing and routes of major human dispersals, the extent to which archaic populations contributed to modern genomes, and how forensic tools developed for ancient samples can be refined to handle increasingly complex ancestry profiles.

Works
67,013
Total citations
790,014
Keywords
Ancient DNAGenomic AnalysisPopulation HistoryHuman EvolutionForensic GeneticsMitochondrial DNA

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