Bacterial Genetics and Biotechnology
Bacterial genetics and biotechnology investigates how bacteria regulate gene expression, maintain cellular equilibrium, and adapt to environmental pressures at the molecular level. Understanding the mechanisms behind processes like signal transduction, RNA-based regulation, and membrane protein function has become especially urgent as antibiotic resistance continues to outpace the development of new therapeutics. Researchers are actively working to decode how bacteria achieve persistence—surviving drug exposure without genetic mutation—and how iron metabolism and other homeostatic systems are coordinated under stress. These questions sit at the intersection of fundamental microbiology and practical medicine, with findings increasingly informing the design of antimicrobial strategies and biotechnological tools.
- Works
- 137,157
- Total citations
- 2,697,841
- Keywords
- Bacterial PhysiologyGene RegulationAntibiotic ResistanceCellular HomeostasisSignal TransductionBacterial Genetics
Top papers in Bacterial Genetics and Biotechnology
Ordered by total citation count.
- DNA sequencing with chain-terminating inhibitors↗ 69,294OA
- MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability↗ 48,185OA
- Prokka: rapid prokaryotic genome annotation↗ 19,527
- One-step inactivation of chromosomal genes in <i>Escherichia coli</i> K-12 using PCR products↗ 15,192OA
- Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors↗ 15,166
- A rapid alkaline extraction procedure for screening recombinant plasmid DNA↗ 14,877OA
- The RAST Server: Rapid Annotations using Subsystems Technology↗ 11,817OA
- Studies on transformation of Escherichia coli with plasmids↗ 11,285
- SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling↗ 11,278
- Systematic Evolution of Ligands by Exponential Enrichment: RNA Ligands to Bacteriophage T4 DNA Polymerase↗ 10,354
- The Phyre2 web portal for protein modeling, prediction and analysis↗ 10,233OA
- RNA-Guided Human Genome Engineering via Cas9↗ 9,379OA
Active researchers
Top authors in this area, ranked by h-index.