Bacterial Genetics and Biotechnology

Bacterial genetics and biotechnology investigates how bacteria regulate gene expression, maintain cellular balance, and respond to environmental signals at the molecular level. Understanding these mechanisms has direct consequences for medicine, because the same regulatory machinery that helps bacteria adapt also underlies antibiotic resistance and the ability of pathogens to persist through treatment. Researchers are currently working to decode how small RNAs, membrane proteins, and signal transduction networks coordinate rapid physiological changes, and how disrupting these pathways might open new therapeutic strategies. Open questions center on the molecular basis of persistence in non-growing cells and how bacteria fine-tune iron metabolism and other homeostatic processes under stress conditions that mimic infection.

Works

138,278

Total citations

2,711,259

Keywords

Bacterial PhysiologyGene RegulationAntibiotic ResistanceCellular HomeostasisSignal TransductionBacterial Genetics