Life SciencesBiochemistry, Genetics and Molecular BiologyGenetics

Genetic and phenotypic traits in livestock

Genomic selection and marker-assisted breeding use an animal's or plant's DNA sequence to predict how well it will perform before it ever expresses a measurable trait, replacing the slow trial-and-error of classical breeding with statistically driven choices made early in an organism's life. By linking thousands of genetic variants across the genome to economically important characteristics—milk yield, disease resistance, feed efficiency—researchers can estimate an individual's breeding value with far greater accuracy and speed than phenotypic records alone allow. Genome-wide association studies and quantitative genetics provide the underlying architecture, revealing which regions of the genome contribute to complex traits shaped by many genes acting in concert with the environment. Open challenges include improving prediction accuracy across breeds and environments where reference populations are small, and understanding how domestication-driven reductions in genetic diversity constrain the long-term response to selection.

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173,691
Total citations
1,879,620
Keywords
Genomic SelectionPlant BreedingAnimal BreedingGenetic Value PredictionMarker-Assisted SelectionQuantitative Genetics

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