Fungal Biology and Applications
Medicinal mushrooms have been used therapeutically for centuries, but only recently has rigorous pharmacological research begun to characterize the specific compounds responsible for their biological effects, particularly the polysaccharides and triterpenes found in species like *Ganoderma lucidum* that appear to modulate immune function and suppress tumor growth. Much of the current work focuses on isolating and standardizing these active constituents, measuring their antioxidant capacity, and understanding how they interact with immune pathways relevant to cancer therapy. Translating these findings into clinical practice remains an active challenge, as researchers work to determine effective dosages, delivery mechanisms, and how fungal compounds might complement or enhance conventional treatments. Open questions center on which molecular targets these agents act upon most directly and whether their immunomodulating effects can be harnessed without unintended systemic consequences.
- Works
- 115,753
- Total citations
- 1,051,868
- Keywords
- Medicinal MushroomsAntioxidant ActivityPolysaccharidesCancer TherapyImmunomodulating CompoundsNutritional Value
Top papers in Fungal Biology and Applications
Ordered by total citation count.
- TOR Signaling in Growth and Metabolism↗ 5,747OA
- The Fusarium Laboratory Manual↗ 4,620
- Signal Transduction by the JNK Group of MAP Kinases↗ 4,210OA
- mTOR: from growth signal integration to cancer, diabetes and ageing↗ 3,936
- A new method which gives an objective measure of colonization of roots by vesicular—arbuscular mycorrhizal fungi↗ 3,856OA
- The UNITE database for molecular identification of fungi: handling dark taxa and parallel taxonomic classifications↗ 3,515OA
- Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human↗ 2,741
- Bioprospecting for Microbial Endophytes and Their Natural Products↗ 2,334OA
- Water relations, drought and vesicular-arbuscular mycorrhizal symbiosis↗ 2,174
- Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides↗ 2,106
- Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive↗ 2,102
- A new fungal phylum, the Glomeromycota: phylogeny and evolution↗ 2,065
Active researchers
Top authors in this area, ranked by h-index.