Fungal Biology and Applications
Certain fungi have been used in traditional medicine for centuries, and contemporary pharmacology is now working to explain why, isolating specific compounds — particularly polysaccharides and triterpenes — that appear to modulate immune function and inhibit tumor growth. Species like *Ganoderma lucidum* have become focal points for this work, with researchers characterizing their antioxidant activity and probing how their bioactive constituents interact with cancer cells and immune pathways at the molecular level. A central challenge is moving from promising laboratory results to clinically validated therapies, which requires understanding how these compounds behave in living systems, how they should be standardized and dosed, and whether they can complement existing cancer treatments rather than simply substitute for them. Active investigation is also expanding beyond a handful of well-studied species, asking whether the medicinal potential seen in a few mushrooms reflects broader patterns across fungal diversity.
- Works
- 117,471
- Total citations
- 1,073,228
- Keywords
- Medicinal MushroomsAntioxidant ActivityPolysaccharidesCancer TherapyImmunomodulating CompoundsNutritional Value
Top papers in Fungal Biology and Applications
Ordered by total citation count.
- TOR Signaling in Growth and Metabolism↗ 5,787OA
- The Fusarium Laboratory Manual↗ 4,682
- Signal Transduction by the JNK Group of MAP Kinases↗ 4,228OA
- mTOR: from growth signal integration to cancer, diabetes and ageing↗ 3,960
- A new method which gives an objective measure of colonization of roots by vesicular—arbuscular mycorrhizal fungi↗ 3,912OA
- The UNITE database for molecular identification of fungi: handling dark taxa and parallel taxonomic classifications↗ 3,652OA
- Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human↗ 2,758
- Bioprospecting for Microbial Endophytes and Their Natural Products↗ 2,357OA
- Water relations, drought and vesicular-arbuscular mycorrhizal symbiosis↗ 2,199
- Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides↗ 2,124
- Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive↗ 2,120
- A new fungal phylum, the Glomeromycota: phylogeny and evolution↗ 2,078
Active researchers
Top authors in this area, ranked by h-index.