Coffee research and impacts
Coffee is one of the most widely consumed beverages in the world, and its primary active compound, caffeine, has measurable effects on the central nervous system, metabolism, and cardiovascular function. Pharmacological research in this area examines how caffeine and co-occurring compounds like chlorogenic acid — a polyphenol with antioxidant properties — influence outcomes ranging from cognitive performance and energy expenditure to the risk of type 2 diabetes and heart disease. The rise of high-dose energy drinks has added urgency to understanding where therapeutic benefit ends and physiological harm begins. Researchers are currently working to clarify how individual variation in caffeine metabolism shapes health outcomes and whether the protective associations seen in observational coffee studies reflect caffeine itself, chlorogenic acid, or some combination of the two.
- Works
- 54,235
- Total citations
- 598,358
- Keywords
- CaffeineCoffeeHealth EffectsEnergy DrinksChlorogenic AcidMetabolism
Top papers in Coffee research and impacts
Ordered by total citation count.
- Ameliorating physical and chemical properties of highly weathered soils in the tropics with charcoal - a review↗ 2,862
- Actions of Caffeine in the Brain with Special Reference to Factors That Contribute to Its Widespread Use↗ 2,607
- HIGH ABSORPTION BUT VERY LOW BIOAVAILABILITY OF ORAL RESVERATROL IN HUMANS↗ 1,814
- Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6↗ 1,621OA
- Chlorogenic acid (CGA): A pharmacological review and call for further research↗ 1,540
- Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects↗ 1,460
- Nicotine Chemistry, Metabolism, Kinetics and Biomarkers↗ 1,414OA
- Hierarchical Scheme for LC-MS<i><sup>n</sup></i> Identification of Chlorogenic Acids↗ 1,240
- Effects of caffeine on human health↗ 1,197
- Spermidine in health and disease↗ 1,090
- Coffee and Health: A Review of Recent Human Research↗ 1,084
- Shade Coffee: A Disappearing Refuge for Biodiversity↗ 1,044OA
Active researchers
Top authors in this area, ranked by h-index.