Coffee research and impacts
Coffee is one of the most widely consumed psychoactive beverages in the world, and pharmacological research has moved well beyond caffeine's well-known stimulant effects to examine how the full chemical profile of coffee — including chlorogenic acids and other polyphenols — shapes metabolism, cardiovascular function, and cognitive performance. Epidemiological and mechanistic studies have linked regular coffee consumption to reduced risk of type 2 diabetes and certain liver conditions, likely through antioxidant activity and modulation of insulin sensitivity, though isolating causation from correlation remains an ongoing methodological challenge. The rapid rise of energy drinks has complicated the picture, introducing higher caffeine doses alongside novel additives whose combined effects are still being characterized. Researchers are now working to clarify which compounds drive which outcomes, how individual genetic variation in caffeine metabolism alters risk and benefit, and whether findings from coffee translate meaningfully to other caffeine-containing products.
- Works
- 55,680
- Total citations
- 604,964
- Keywords
- CaffeineCoffeeHealth EffectsEnergy DrinksChlorogenic AcidMetabolism
Top papers in Coffee research and impacts
Ordered by total citation count.
- Ameliorating physical and chemical properties of highly weathered soils in the tropics with charcoal - a review↗ 2,874
- Actions of Caffeine in the Brain with Special Reference to Factors That Contribute to Its Widespread Use↗ 2,620
- HIGH ABSORPTION BUT VERY LOW BIOAVAILABILITY OF ORAL RESVERATROL IN HUMANS↗ 1,834
- Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6↗ 1,633OA
- Chlorogenic acid (CGA): A pharmacological review and call for further research↗ 1,555
- Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects↗ 1,465
- Nicotine Chemistry, Metabolism, Kinetics and Biomarkers↗ 1,426OA
- Hierarchical Scheme for LC-MS<i><sup>n</sup></i> Identification of Chlorogenic Acids↗ 1,244
- Effects of caffeine on human health↗ 1,201
- Spermidine in health and disease↗ 1,127
- Coffee and Health: A Review of Recent Human Research↗ 1,087
- Shade Coffee: A Disappearing Refuge for Biodiversity↗ 1,048OA
Active researchers
Top authors in this area, ranked by h-index.