Epilepsy research and treatment
Epilepsy is a neurological condition defined by recurrent, unprovoked seizures, and understanding it requires tracing how abnormal electrical activity arises in the brain, spreads, and can be interrupted. Researchers work to refine how seizures are classified, develop antiepileptic drugs that suppress this activity with fewer side effects, and identify why roughly a third of patients remain resistant to medication entirely. When seizures become prolonged or continuous—a dangerous state called status epilepticus—rapid intervention is critical, and determining the best protocols remains an active clinical problem. Emerging work on neuroinflammation, genetics, and surgical targeting is reshaping how clinicians think about both the causes of epilepsy and what it might take to achieve lasting remission.
- Works
- 163,358
- Total citations
- 2,487,268
- Keywords
- EpilepsySeizuresClassificationAntiepileptic DrugsStatus EpilepticusNeurobiology
Top papers in Epilepsy research and treatment
Ordered by total citation count.
- Modification of seizure activity by electrical stimulation: II. Motor seizure↗ 7,237
- ILAE Official Report: A practical clinical definition of epilepsy↗ 5,998OA
- Proposal for Revised Classification of Epilepsies and Epileptic Syndromes↗ 5,365
- Early Identification of Refractory Epilepsy↗ 5,191OA
- <scp>ILAE</scp> classification of the epilepsies: Position paper of the <scp>ILAE</scp> Commission for Classification and Terminology↗ 4,947OA
- Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog Synthesis↗ 4,901
- Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies↗ 4,803
- The Neuropsychological Assessment↗ 4,396
- Revised terminology and concepts for organization of seizures and epilepsies: Report of the ILAE Commission on Classification and Terminology, 2005–2009↗ 4,371
- Epileptic Seizures and Epilepsy: Definitions Proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE)↗ 3,632OA
- A Randomized Controlled Trial of Surgery for Temporal Lobe Epilepsy↗ 3,514OA
- Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies↗ 3,493OA
Active researchers
Top authors in this area, ranked by h-index.