Dementia and Cognitive Impairment Research
Dementia research investigates how and why the brain loses its capacity for memory, reasoning, and everyday function over time, with Alzheimer's disease representing the most common and intensively studied form. Scientists use neuroimaging and molecular biomarkers to detect biological changes that often precede noticeable symptoms by years, raising the possibility of earlier intervention before significant damage occurs. A central open question is whether mild cognitive impairment — a measurable but not yet disabling decline — reliably predicts full dementia, or whether some individuals stabilize or recover, which has direct consequences for how clinicians counsel patients and families. Alongside the biological work, researchers are increasingly quantifying the psychological and economic strain on caregivers, recognizing that the disease's burden extends well beyond the person diagnosed.
- Works
- 151,719
- Total citations
- 3,783,938
- Keywords
- Alzheimer's DiseaseMild Cognitive ImpairmentDementiaNeuroimagingCognitive DeclineBiomarkers
Top papers in Dementia and Cognitive Impairment Research
Ordered by total citation count.
- The Pittsburgh sleep quality index: A new instrument for psychiatric practice and research↗ 34,632
- Clinical diagnosis of Alzheimer's disease↗ 27,985OA
- The Montreal Cognitive Assessment, MoCA: A Brief Screening Tool For Mild Cognitive Impairment↗ 25,356
- [Japanese version of the Neuropsychiatric Inventory--a scoring system for neuropsychiatric disturbance in dementia patients].↗ 20,872
- Special Care Units and Traditional Care in Dementia: Relationship with Behavior, Cognition, Functional Status and Quality of Life - A Review↗ 20,660OA
- The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease↗ 18,808OA
- Neuropathological stageing of Alzheimer-related changes↗ 16,298
- Development and validation of a geriatric depression screening scale: A preliminary report↗ 15,028OA
- Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy↗ 10,400OA
- NIA‐AA Research Framework: Toward a biological definition of Alzheimer's disease↗ 10,354OA
- Dementia prevention, intervention, and care: 2020 report of the Lancet Commission↗ 10,231OA
- The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease↗ 10,169
Active researchers
Top authors in this area, ranked by h-index.