Viral gastroenteritis research and epidemiology

Viral gastroenteritis — intestinal infection causing diarrhea, vomiting, and dehydration — is responsible for hundreds of thousands of child deaths each year, with rotavirus and norovirus accounting for the largest share of that burden globally. Researchers track how these viruses spread across populations, how their genetic strains evolve over time, and how the introduction of rotavirus vaccines has shifted disease patterns in different regions. A central challenge is the extraordinary diversity of circulating strains: norovirus in particular mutates rapidly, complicating efforts to develop durable vaccines and making molecular genotyping essential for surveillance. Active work is focused on understanding why vaccine effectiveness varies between high- and low-income settings, and on identifying which viral and host factors drive the most severe outcomes.

Works

95,442

Total citations

1,557,607

Keywords

RotavirusNorovirusGastroenteritisVaccineInfectionEpidemiology