Uterine Myomas and Treatments
Uterine myomas, also called leiomyomas or fibroids, are benign smooth-muscle tumors of the uterus that affect a substantial proportion of women of reproductive age and rank among the most common reasons for gynecological surgery. Researchers study their hormonal drivers—particularly the role of progesterone in promoting tumor growth—alongside a spectrum of interventions ranging from hysterectomy and myomectomy to minimally invasive options such as uterine artery embolization and MRI-guided focused ultrasound. A central challenge is balancing effective symptom relief against the preservation of fertility and quality of life, especially since some treatments carry meaningful tradeoffs for reproductive outcomes. Open questions include reliably distinguishing benign myomas from the rare but aggressive uterine sarcomas before surgery, and identifying which patients will respond best to specific treatment modalities based on tumor biology and epidemiological risk factors.
- Works
- 70,577
- Total citations
- 636,104
- Keywords
- Uterine LeiomyomaUterine FibroidsHysterectomyUterine SarcomasUterine Artery EmbolizationReproductive Outcomes
Top papers in Uterine Myomas and Treatments
Ordered by total citation count.
- Effects of Conjugated Equine Estrogen in Postmenopausal Women With Hysterectomy↗ 4,466OA
- Endometriosis↗ 3,025
- Revised American Society for Reproductive Medicine classification of endometriosis: 1996↗ 2,980
- High cumulative incidence of uterine leiomyoma in black and white women: Ultrasound evidence↗ 2,428
- Endometriosis↗ 2,114
- Endometriosis: pathogenesis and treatment↗ 1,935
- Endometriosis↗ 1,924
- Minimally Invasive versus Abdominal Radical Hysterectomy for Cervical Cancer↗ 1,869OA
- The American Fertility Society classifications of adnexal adhesions, distal tubal occlusion, tubal occlusion secondary to tubal ligation, tubal pregnancies, Müllerian anomalies and intrauterine adhesions↗ 1,842
- Surgical approach to hysterectomy for benign gynaecological disease↗ 1,822OA
- Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: multicentre randomised trial↗ 1,764
- Endometriosis↗ 1,743
Active researchers
Top authors in this area, ranked by h-index.