Endometrial and Cervical Cancer Treatments

Endometrial and cervical cancers are among the most common gynecologic malignancies, and improving how they are staged, classified, and treated has direct consequences for survival and quality of life in millions of patients. Research in this area spans molecular profiling of tumors to identify which patients need aggressive treatment, surgical approaches such as robotic-assisted procedures and sentinel lymph node biopsy to minimize harm while preserving accuracy, and radiation strategies including brachytherapy and chemoradiotherapy that target residual or locally advanced disease. A central open question is how molecular classification—which divides endometrial carcinoma into distinct subtypes with different prognoses—should reshape decisions about chemotherapy and radiation in routine clinical practice. Ongoing work is also refining when and how to de-escalate treatment for lower-risk patients without compromising outcomes, balancing the goal of cure against the long-term toxicities of aggressive intervention.

Works

85,648

Total citations

1,031,979

Keywords

Endometrial CarcinomaCervical CancerBrachytherapyRadiation TherapyMolecular ClassificationSentinel Lymph Node Biopsy