Health SciencesMedicineCardiology and Cardiovascular Medicine

Heart Failure Treatment and Management

Heart failure is a clinical syndrome in which the heart cannot pump enough blood to meet the body's demands, affecting tens of millions of people worldwide and accounting for a substantial share of cardiovascular hospitalizations and deaths. Researchers study how to diagnose the condition reliably—using tools like B-type natriuretic peptide, a hormone the stressed heart releases in measurable quantities—and how to translate treatment guidelines into consistent real-world care that reduces both mortality and the high rates of hospital readmission that burden patients and health systems alike. A persistent challenge is understanding how complicating factors, particularly declining kidney function, alter disease progression and blunt the effectiveness of standard therapies. Active work focuses on refining risk prediction models that can identify which patients are most likely to deteriorate, and on closing the gap between what clinical trials demonstrate and what patients actually receive.

Works
101,723
Total citations
1,949,064
Keywords
Heart FailureGuidelinesDiagnosisTreatmentB-Type Natriuretic PeptideEpidemiology

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