Acute Myocardial Infarction Research
Acute myocardial infarction occurs when a coronary artery becomes suddenly blocked, cutting off blood supply to the heart muscle and triggering a cascade of damage that can be fatal within hours if untreated. Research in this area covers how to rapidly identify a heart attack—using biomarkers like troponin and electrocardiographic patterns such as ST-segment elevation—and how to restore blood flow as quickly as possible, whether through clot-dissolving drugs or mechanical procedures like primary angioplasty. Clinical guidelines synthesize this evidence into treatment protocols that shape care worldwide, yet significant questions remain around optimizing reperfusion timing, selecting patients for specific interventions, and managing the subset who present without classic diagnostic findings. Active work is also focused on reducing the long-term risk of recurrence and heart failure in survivors, as myocardial infarction remains one of the leading causes of death and disability globally.
- Works
- 85,642
- Total citations
- 1,560,492
- Keywords
- Myocardial InfarctionAcute Coronary SyndromesST-Segment ElevationPrimary AngioplastyTroponin AssaysCardiovascular Disease
Top papers in Acute Myocardial Infarction Research
Ordered by total citation count.
- Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study↗ 11,954OA
- 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation↗ 9,756OA
- ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction—Executive Summary↗ 8,376
- 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation↗ 8,314OA
- 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes↗ 7,125OA
- Mortality from Coronary Heart Disease in Subjects with Type 2 Diabetes and in Nondiabetic Subjects with and without Prior Myocardial Infarction↗ 7,069OA
- Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes↗ 7,066OA
- Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients↗ 6,960OA
- Prophylactic Implantation of a Defibrillator in Patients with Myocardial Infarction and Reduced Ejection Fraction↗ 6,870OA
- ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation↗ 6,842OA
- Prasugrel versus Clopidogrel in Patients with Acute Coronary Syndromes↗ 6,745OA
- A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)↗ 6,527
Active researchers
Top authors in this area, ranked by h-index.