Cardiac Valve Diseases and Treatments
The heart's four valves open and close roughly 100,000 times a day, and when they narrow or leak—conditions known as aortic stenosis and mitral regurgitation—the consequences range from progressive heart failure to sudden death. Cardiologists and cardiac surgeons have developed two main repair strategies: open surgical valve replacement, the long-standing standard, and transcatheter approaches that thread a new valve through a catheter without cracking the chest, expanding treatment options to patients once considered too frail for surgery. Echocardiography serves as the cornerstone for diagnosing severity, timing intervention, and evaluating how prosthetic valves perform over time, though standardizing these measurements across institutions remains an active area of guideline development. Key open questions include determining the optimal timing of intervention in patients with moderate but asymptomatic disease, understanding the long-term durability of transcatheter valves relative to surgical ones, and refining surgical risk models so that the right procedure is matched to the right patient.
- Works
- 179,182
- Total citations
- 1,988,491
- Keywords
- Transcatheter Aortic-Valve ReplacementSurgical Aortic-Valve ReplacementValvular RegurgitationEchocardiography GuidelinesAortic StenosisMitral Regurgitation
Top papers in Cardiac Valve Diseases and Treatments
Ordered by total citation count.
- Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging↗ 18,194OA
- Recommendations for Chamber Quantification: A Report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, Developed in Conjunction with the European Association of Echocardiography, a Branch of the European Society of Cardiology↗ 11,360
- ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease↗ 8,514OA
- Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging↗ 8,399OA
- Recommendations for Quantitation of the Left Ventricle by Two-Dimensional Echocardiography↗ 8,145
- The Effect of Pravastatin on Coronary Events after Myocardial Infarction in Patients with Average Cholesterol Levels↗ 7,496OA
- Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery↗ 7,201OA
- Standardized Myocardial Segmentation and Nomenclature for Tomographic Imaging of the Heart↗ 6,996
- Transcatheter versus Surgical Aortic-Valve Replacement in High-Risk Patients↗ 6,353OA
- 2017 ESC/EACTS Guidelines for the management of valvular heart disease↗ 6,328OA
- 2021 ESC/EACTS Guidelines for the management of valvular heart disease↗ 5,558OA
- Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients↗ 5,059OA
Active researchers
Top authors in this area, ranked by h-index.