Cardiac Valve Diseases and Treatments
Cardiac valve diseases occur when one or more of the heart's four valves fails to open or close properly, either narrowing to restrict blood flow—as in aortic stenosis—or leaking in reverse, as in mitral regurgitation. Both conditions force the heart to work harder over time, eventually leading to heart failure or death if left untreated, which is why accurate diagnosis through echocardiography and timely intervention are central concerns. Over the past two decades, transcatheter aortic-valve replacement has transformed care by offering a less invasive alternative to open surgery, extending treatment to patients once considered too high-risk for an operation. Active research continues to refine which patients benefit most from each approach, how to evaluate the long-term durability of prosthetic valves, and how best to time intervention in patients with moderate or asymptomatic disease before irreversible cardiac damage sets in.
- Works
- 177,481
- Total citations
- 1,974,438
- Keywords
- Transcatheter Aortic-Valve ReplacementSurgical Aortic-Valve ReplacementValvular RegurgitationEchocardiography GuidelinesAortic StenosisMitral Regurgitation
Top papers in Cardiac Valve Diseases and Treatments
Ordered by total citation count.
- Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging↗ 18,008OA
- Recommendations for Chamber Quantification: A Report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, Developed in Conjunction with the European Association of Echocardiography, a Branch of the European Society of Cardiology↗ 11,333
- ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease↗ 8,511OA
- Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging↗ 8,304OA
- Recommendations for Quantitation of the Left Ventricle by Two-Dimensional Echocardiography↗ 8,141
- The Effect of Pravastatin on Coronary Events after Myocardial Infarction in Patients with Average Cholesterol Levels↗ 7,491OA
- Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery↗ 7,158OA
- Standardized Myocardial Segmentation and Nomenclature for Tomographic Imaging of the Heart↗ 6,965
- Transcatheter versus Surgical Aortic-Valve Replacement in High-Risk Patients↗ 6,321OA
- 2017 ESC/EACTS Guidelines for the management of valvular heart disease↗ 6,311OA
- 2021 ESC/EACTS Guidelines for the management of valvular heart disease↗ 5,451OA
- Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients↗ 5,028OA
Active researchers
Top authors in this area, ranked by h-index.