Coronary Interventions and Diagnostics
Coronary interventions and diagnostics center on how physicians detect, measure, and mechanically treat blockages in the arteries that supply blood to the heart muscle, most often caused by the gradual buildup of fatty plaques known as atherosclerosis. The core procedure, percutaneous coronary intervention, involves threading a catheter to the site of narrowing and deploying a small metal scaffold called a stent — increasingly coated with drugs that slow tissue regrowth and reduce the risk of re-blockage. Researchers are actively working out when intervention actually improves outcomes over medication alone, using pressure-based measurements like fractional flow reserve and high-resolution imaging tools like intravascular ultrasound to better characterize which plaques are genuinely dangerous before they rupture. Questions around how long patients need blood-thinning therapy after stent placement, and how to identify vulnerable plaques before they cause a heart attack, remain among the most consequential open problems in the area.
- Works
- 108,705
- Total citations
- 1,619,676
- Keywords
- Coronary StentsMyocardial RevascularizationDrug-Eluting StentsPercutaneous Coronary InterventionAtherosclerosisFractional Flow Reserve
Top papers in Coronary Interventions and Diagnostics
Ordered by total citation count.
- Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II)↗ 8,136OA
- 2018 ESC/EACTS Guidelines on myocardial revascularization↗ 7,032OA
- Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials↗ 6,386OA
- Clinical End Points in Coronary Stent Trials↗ 5,404
- 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation↗ 4,978OA
- Optimal Medical Therapy with or without PCI for Stable Coronary Disease↗ 4,680OA
- A Comparison of Balloon-Expandable-Stent Implantation with Balloon Angioplasty in Patients with Coronary Artery Disease↗ 4,546OA
- ACC/AHA Guidelines for the Management of Patients With Unstable Angina and Non–ST-Segment Elevation Myocardial Infarction: Executive Summary and Recommendations↗ 4,513OA
- Standardized Bleeding Definitions for Cardiovascular Clinical Trials↗ 4,382
- Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials↗ 4,343
- Percutaneous Coronary Intervention versus Coronary-Artery Bypass Grafting for Severe Coronary Artery Disease↗ 4,325OA
- 2014 ESC/EACTS Guidelines on myocardial revascularization↗ 4,315OA
Active researchers
Top authors in this area, ranked by h-index.