Acute Ischemic Stroke Management
Acute ischemic stroke occurs when a clot blocks blood flow to part of the brain, and how quickly and effectively that blockage is treated determines how much brain tissue survives. Epidemiologists and clinicians study who gets strokes and why, how treatments like clot-dissolving drugs and catheter-based clot removal perform across different populations, and what long-term outcomes look like after the acute event. Despite real progress in revascularization techniques and prevention guidelines, stroke remains a leading cause of death and disability worldwide, with substantial disparities in access to time-sensitive care. Active research is now pressing on two fronts: identifying patients who might benefit from treatment outside current time windows, and finding neuroprotective strategies that can shield brain tissue while circulation is being restored.
- Works
- 133,496
- Total citations
- 2,024,785
- Keywords
- Ischemic StrokeThrombolysisEndovascular TherapyRisk FactorsPrevention GuidelinesClinical Outcomes
Top papers in Acute Ischemic Stroke Management
Ordered by total citation count.
- Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment.↗ 12,182OA
- Correspondence - Tranexamic acid for traumatic brain injury↗ 11,729OA
- Tissue Plasminogen Activator for Acute Ischemic Stroke↗ 11,642
- Aspirin plus Clopidogrel as Secondary Prevention after Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis↗ 11,554OA
- Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies↗ 10,203
- Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation↗ 9,349OA
- Heart disease and stroke statistics--2015 update: a report from the American Heart Association.↗ 8,337
- Guidelines for the Early Management of Patients With Acute Ischemic Stroke↗ 7,643OA
- Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials↗ 7,470
- Reversible middle cerebral artery occlusion without craniectomy in rats.↗ 7,447OA
- Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019↗ 7,355OA
- Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association↗ 7,111
Active researchers
Top authors in this area, ranked by h-index.