Acute Ischemic Stroke Management
Acute ischemic stroke occurs when a clot blocks blood flow to part of the brain, and the epidemiology of this condition examines who is affected, why, and with what consequences across populations worldwide. Researchers track how risk factors such as hypertension, atrial fibrillation, and diabetes translate into stroke incidence and mortality, while also evaluating how treatments like thrombolysis and endovascular clot removal alter those outcomes at a population level. Despite major advances in revascularization, substantial questions remain about how to extend effective treatment windows, reduce the global disparity in access to stroke care, and identify neuroprotective strategies that can limit brain injury when reperfusion arrives late or incompletely. Understanding the full burden of stroke—who survives, who recovers, and who is left disabled—continues to drive prevention guidelines and shape how health systems allocate resources.
- Works
- 135,377
- Total citations
- 2,043,906
- Keywords
- Ischemic StrokeThrombolysisEndovascular TherapyRisk FactorsPrevention GuidelinesClinical Outcomes
Top papers in Acute Ischemic Stroke Management
Ordered by total citation count.
- Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment.↗ 12,274OA
- Correspondence - Tranexamic acid for traumatic brain injury↗ 11,771OA
- Tissue Plasminogen Activator for Acute Ischemic Stroke↗ 11,664
- Aspirin plus Clopidogrel as Secondary Prevention after Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis↗ 11,556OA
- Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies↗ 10,248
- Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation↗ 9,397OA
- Heart disease and stroke statistics--2015 update: a report from the American Heart Association.↗ 8,337
- Guidelines for the Early Management of Patients With Acute Ischemic Stroke↗ 7,656OA
- Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials↗ 7,601
- Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019↗ 7,576OA
- Reversible middle cerebral artery occlusion without craniectomy in rats.↗ 7,498OA
- Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association↗ 7,257
Active researchers
Top authors in this area, ranked by h-index.