Health SciencesMedicineDermatology

Acne and Rosacea Treatments and Effects

Acne vulgaris and rosacea are among the most prevalent chronic inflammatory skin conditions, affecting hundreds of millions of people worldwide and ranging from mild cosmetic concerns to disfiguring disease with serious psychological impact. Research into their origins focuses on the interplay between the skin's sebaceous glands, the bacterium *Propionibacterium acnes*, and the immune responses that drive persistent inflammation. Current treatments span topical retinoids and antibiotics to photodynamic therapy and biologics, but rising antibiotic resistance and incomplete understanding of rosacea's underlying triggers leave substantial gaps in long-term management. Active work is directed at clarifying the precise microbial and genetic factors that determine why some patients respond well to existing therapies while others experience relapsing or treatment-resistant disease.

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47,106
Total citations
454,776
Keywords
Acne VulgarisRosaceaPropionibacterium AcnesPathogenesisTreatmentInflammation

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