Spinal Cord Injury Research
Spinal cord injury disrupts the neural pathways that carry motor and sensory signals between the brain and body, producing deficits that range from partial weakness to complete paralysis depending on where and how severely the cord is damaged. Researchers work to understand the biological cascade that unfolds after injury — including inflammation, cell death, and the limited capacity of spinal neurons to regenerate — in order to identify points where intervention might preserve or restore function. Standardized neurological classification systems help track recovery across patients and make clinical trials comparable, though questions remain about which therapeutic windows matter most and how interventions like neuroprotective drugs, neuromodulation, and structured physical activity interact to drive functional gains. A central open challenge is translating promising laboratory findings into treatments that reliably improve outcomes in the diverse population of people living with spinal cord injury.
- Works
- 53,449
- Total citations
- 1,038,353
- Keywords
- Spinal Cord InjuryNeurological ClassificationEpidemiologyRecoveryInflammationNeuroprotection
Top papers in Spinal Cord Injury Research
Ordered by total citation count.
- A Sensitive and Reliable Locomotor Rating Scale for Open Field Testing in Rats↗ 4,550
- Alterations in Brain and Immune Function Produced by Mindfulness Meditation↗ 2,927
- Global estimates of the need for rehabilitation based on the Global Burden of Disease study 2019: a systematic analysis for the Global Burden of Disease Study 2019↗ 2,847OA
- A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury↗ 2,751OA
- Traumatic spinal cord injury↗ 2,401
- Chondroitinase ABC promotes functional recovery after spinal cord injury↗ 2,361
- International standards for neurological classification of spinal cord injury (Revised 2011)↗ 2,331OA
- Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord↗ 2,166OA
- Targeting Recovery: Priorities of the Spinal Cord-Injured Population↗ 2,117
- International Standards for Neurological and Functional Classification of Spinal Cord Injury↗ 2,056OA
- Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016↗ 2,014OA
- Spinal-cord injury↗ 1,807
Active researchers
Top authors in this area, ranked by h-index.