Health SciencesMedicinePathology and Forensic Medicine

Breast Lesions and Carcinomas

Breast pathology examines the structural and cellular changes that occur in breast tissue, from benign lesions to malignant carcinomas, using tools that span imaging—mammography and ultrasound—through to histological analysis of biopsied material. Accurate diagnosis depends on integrating these modalities, since many lesions appear ambiguous until tissue is examined under the microscope, and certain rare subtypes like metaplastic carcinoma and phyllodes tumors present classification and treatment challenges that standard protocols handle poorly. A central open question is how to reduce both overdiagnosis of indolent lesions and underdiagnosis of aggressive ones, particularly as screening programs expand into younger and higher-risk populations. Ongoing research focuses on refining biopsy criteria, improving imaging resolution, and developing molecular markers that can better predict which lesions will progress and which will remain clinically insignificant.

Works
53,692
Total citations
539,571
Keywords
Breast CancerMammographyUltrasoundPathologyLesionsBiopsy

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