Breast Lesions and Carcinomas
Breast pathology examines the structural and cellular changes that occur in breast tissue, from benign lesions to malignant carcinomas, using tools that span imaging—mammography and ultrasound—through to histological analysis of biopsied material. Accurate diagnosis depends on integrating these modalities, since many lesions appear ambiguous until tissue is examined under the microscope, and certain rare subtypes like metaplastic carcinoma and phyllodes tumors present classification and treatment challenges that standard protocols handle poorly. A central open question is how to reduce both overdiagnosis of indolent lesions and underdiagnosis of aggressive ones, particularly as screening programs expand into younger and higher-risk populations. Ongoing research focuses on refining biopsy criteria, improving imaging resolution, and developing molecular markers that can better predict which lesions will progress and which will remain clinically insignificant.
- Works
- 53,692
- Total citations
- 539,571
- Keywords
- Breast CancerMammographyUltrasoundPathologyLesionsBiopsy
Top papers in Breast Lesions and Carcinomas
Ordered by total citation count.
- Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer↗ 13,213OA
- Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials↗ 7,604
- A Gene-Expression Signature as a Predictor of Survival in Breast Cancer↗ 6,513OA
- A Multigene Assay to Predict Recurrence of Tamoxifen-Treated, Node-Negative Breast Cancer↗ 6,334OA
- Twenty-Year Follow-up of a Randomized Trial Comparing Total Mastectomy, Lumpectomy, and Lumpectomy plus Irradiation for the Treatment of Invasive Breast Cancer↗ 6,187OA
- pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long‐term follow‐up↗ 6,174
- Trastuzumab plus Adjuvant Chemotherapy for Operable HER2-Positive Breast Cancer↗ 5,344OA
- Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials↗ 5,112
- Twenty-Year Follow-up of a Randomized Study Comparing Breast-Conserving Surgery with Radical Mastectomy for Early Breast Cancer↗ 4,419OA
- Ki67 expression in breast cancer↗ 4,396OA
- Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10 801 women in 17 randomised trials↗ 3,895OA
- Strategies for subtypes—dealing with the diversity of breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011↗ 3,867OA
Active researchers
Top authors in this area, ranked by h-index.