Electrospun Nanofibers in Biomedical Applications

Electrospinning uses a high-voltage electric field to draw polymer solutions into fibers with diameters ranging from tens of nanometers to a few micrometers, producing meshes whose structure closely resembles the fibrous architecture of natural tissue. Researchers in this area study how the composition, geometry, and surface chemistry of these fibers can be tuned to support cell growth, guide tissue regeneration, or control the release of therapeutic drugs over time. Because the fibers offer an exceptionally high surface-area-to-volume ratio and can incorporate bioactive molecules or nanoparticles, they are actively being explored for applications ranging from wound dressings and vascular grafts to bone and neural scaffolds. Key open questions include how to scale fabrication while preserving fiber uniformity, how to achieve precise spatial control over drug release kinetics, and how electrospun constructs perform under the mechanical demands of living tissue over long periods.

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84,664

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Keywords

ElectrospinningNanofibersTissue EngineeringBiomedical ApplicationsPolymer NanofibersDrug Delivery