Electrospun Nanofibers in Biomedical Applications

Electrospinning is a fabrication technique that uses high-voltage electric fields to draw polymer solutions into fibers with diameters ranging from tens of nanometers to a few micrometers, producing structures that closely mimic the fibrous architecture of natural tissue. Researchers working with these materials investigate how fiber diameter, alignment, porosity, and surface chemistry influence how cells adhere, proliferate, and differentiate — properties that make electrospun scaffolds promising for repairing bone, skin, cartilage, and vascular tissue, as well as for controlled drug release. A persistent challenge is translating constructs that perform well in vitro into implantable devices that remain mechanically stable, degrade predictably, and integrate safely with living tissue over time. Active directions include embedding bioactive molecules or nanoparticles directly into fibers to create multifunctional nanocomposites, and developing scalable spinning processes that can produce clinically relevant material quantities without sacrificing structural precision.

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84,115

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1,906,427

Keywords

ElectrospinningNanofibersTissue EngineeringBiomedical ApplicationsPolymer NanofibersDrug Delivery