Electrospun Nanofibers in Biomedical Applications

Electrospinning uses an electric field to draw polymer solutions into fibers with diameters in the nanometer range, producing scaffolds whose fine-scale architecture closely mimics the fibrous structure of natural tissue. Researchers work with these materials across wound healing, bone and cartilage repair, and controlled drug release, where the high surface-area-to-volume ratio and tunable porosity of the resulting mats offer practical advantages over conventional fabrication methods. Active work centers on improving how living cells colonize and remodel synthetic scaffolds, as well as on incorporating nanoparticles or bioactive molecules directly into fibers to create multifunctional composites. A central open question is how to translate laboratory-scale electrospun constructs into reproducible, clinically viable devices while maintaining precise control over fiber geometry and degradation behavior.

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Keywords

ElectrospinningNanofibersTissue EngineeringBiomedical ApplicationsPolymer NanofibersDrug Delivery