Physical SciencesMaterials ScienceBiomaterials

Calcium Carbonate Crystallization and Inhibition

Calcium carbonate crystallization and its inhibition sit at the intersection of materials science and biology, examining how organisms like mollusks and sea urchins grow hard, precisely structured minerals under mild conditions that synthetic processes struggle to replicate. Researchers study how proteins, polysaccharides, and other organic molecules control when and where crystals nucleate, how fast they grow, and what shapes and polymorphs they take—insights that inform the design of bioinspired nanocomposites with exceptional toughness and damage resistance relative to their weight. A central challenge is understanding the nanoscale architecture of natural materials like nacre, where alternating organic and mineral layers produce mechanical properties far superior to those of pure calcium carbonate alone. Active work focuses on translating these hierarchical design principles into synthetic materials for bone repair, protective coatings, and scaled manufacturing, while fundamental questions remain about the molecular mechanisms by which organisms suppress unwanted crystallization or switch between mineral phases on demand.

Works
56,973
Total citations
794,340
Keywords
BiomineralizationBioinspired MaterialsNanocompositesCrystallizationMechanical PropertiesNanoscale Structure

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