Breast Cancer Treatment Studies
Breast cancer is not a single disease but a collection of molecularly distinct subtypes, each defined by characteristic patterns of gene expression and hormone receptor activity that shape how tumors behave and respond to treatment. Researchers in this area work to identify prognostic markers — measurable biological signals that predict whether a patient's cancer is likely to recur or spread — and to understand why some tumors respond well to neoadjuvant therapy or radiotherapy while others do not. A central challenge is translating molecular profiles into reliable clinical guidelines that can guide treatment decisions before surgery, sparing patients from ineffective regimens and unnecessary side effects. Active work is focused on refining the classification of molecular subtypes, discovering new biomarkers that predict treatment response with greater precision, and integrating genomic data into standard care.
- Works
- 120,880
- Total citations
- 2,030,868
- Keywords
- Gene ExpressionBreast TumoursTreatment ResponseMolecular SubtypesPrognostic MarkersNeoadjuvant Therapy
Top papers in Breast Cancer Treatment Studies
Ordered by total citation count.
- New Guidelines to Evaluate the Response to Treatment in Solid Tumors↗ 15,740
- Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer↗ 13,214OA
- Use of Chemotherapy plus a Monoclonal Antibody against HER2 for Metastatic Breast Cancer That Overexpresses HER2↗ 11,554OA
- Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications↗ 10,962OA
- Gene expression profiling predicts clinical outcome of breast cancer↗ 9,622OA
- Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials↗ 7,634
- The Eighth Edition <scp>AJCC</scp> Cancer Staging Manual: Continuing to build a bridge from a population‐based to a more “personalized” approach to cancer staging↗ 6,590OA
- A Gene-Expression Signature as a Predictor of Survival in Breast Cancer↗ 6,534OA
- A Multigene Assay to Predict Recurrence of Tamoxifen-Treated, Node-Negative Breast Cancer↗ 6,383OA
- Twenty-Year Follow-up of a Randomized Trial Comparing Total Mastectomy, Lumpectomy, and Lumpectomy plus Irradiation for the Treatment of Invasive Breast Cancer↗ 6,262OA
- pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long‐term follow‐up↗ 6,210
- Tamoxifen for Prevention of Breast Cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study↗ 5,519OA
Active researchers
Top authors in this area, ranked by h-index.