Spectroscopy Techniques in Biomedical and Chemical Research
Spectroscopy techniques such as Raman and infrared spectroscopy probe how molecules interact with light to reveal chemical composition without destroying the sample, making them especially powerful for studying biological tissues, proteins, and metabolites at fine spatial resolution. In biomedical research, these methods are used to identify cancerous tissue, track glucose levels in blood, and map the molecular architecture of cells and protein assemblies in ways that conventional imaging cannot easily match. Coherent Anti-Stokes Raman Scattering microscopy has pushed the approach further by enabling rapid, label-free chemical imaging of living specimens with enough speed and sensitivity for clinical-adjacent applications. Active work now centers on improving signal reliability in complex biological environments, miniaturizing devices for point-of-care diagnostics, and determining how consistently spectral signatures can distinguish disease states across diverse patient populations.
- Works
- 76,199
- Total citations
- 874,873
- Keywords
- Raman SpectroscopyInfrared SpectroscopyBiomedical ImagingProtein AnalysisChemical ImagingTissue Diagnosis
Top papers in Spectroscopy Techniques in Biomedical and Chemical Research
Ordered by total citation count.
- Single Molecule Detection Using Surface-Enhanced Raman Scattering (SERS)↗ 6,693
- The Principles of Nonlinear Optics↗ 5,122
- Raman microspectroscopy of soot and related carbonaceous materials: Spectral analysis and structural information↗ 4,630
- Determination of Glucose in Blood Using Glucose Oxidase with an Alternative Oxygen Acceptor↗ 4,598
- Principles of Nonlinear Optical Spectroscopy↗ 4,594
- The Quantum Theory of Optical Coherence↗ 3,997OA
- Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance↗ 3,901OA
- Optical properties of biological tissues: a review↗ 3,793
- Standard Normal Variate Transformation and De-Trending of Near-Infrared Diffuse Reflectance Spectra↗ 3,668
- Shell-isolated nanoparticle-enhanced Raman spectroscopy↗ 3,471
- Transdermal drug delivery↗ 3,354OA
- Use of proteomic patterns in serum to identify ovarian cancer↗ 3,252
Active researchers
Top authors in this area, ranked by h-index.