Physical SciencesMaterials ScienceSurfaces, Coatings and Films

Polymer Surface Interaction Studies

Polymer surface interaction studies examine how macromolecules adhere to, organize on, and modify solid surfaces — work that has gained significant momentum from discoveries about how mussels cling to wet rocks using dopamine-rich proteins. Polydopamine, a synthetic mimic of these adhesive proteins, can coat nearly any surface and serve as a platform for attaching antifouling layers, polymer brushes, or biomedical functional groups, making it unusually versatile across applications from implantable devices to marine coatings. A central challenge is understanding exactly how polydopamine forms and polymerizes, since its precise molecular structure remains contested, which complicates rational design of coatings with predictable properties. Researchers are also actively working to balance competing surface demands — such as resisting protein adsorption while still allowing controlled biological interactions — through strategies like zwitterionic materials and layer-by-layer assembly.

Works
46,180
Total citations
1,363,137
Keywords
Mussel-InspiredSurface ChemistryPolydopamineAntifouling CoatingsBiomedical ApplicationsPolymer Brushes

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