Health SciencesMedicineRadiology, Nuclear Medicine and Imaging

Plasma Applications and Diagnostics

Plasma medicine investigates how ionized gas — particularly cold atmospheric plasma, which operates near room temperature — interacts with living tissue through the selective delivery of reactive chemical species such as free radicals and reactive oxygen and nitrogen compounds. Because these species can disrupt bacterial membranes, trigger apoptosis in tumor cells, or accelerate wound healing without the thermal damage associated with conventional plasma, researchers are exploring clinical uses ranging from sterilization of drug-resistant infections to targeted cancer therapy. A central open question is how to control the dose and composition of reactive species precisely enough to distinguish between desired therapeutic effects and unintended damage to healthy tissue. Ongoing work is also mapping the signaling pathways through which plasma-generated chemistry influences cell behavior, which could eventually allow treatments to be tuned at the molecular level rather than calibrated by trial and error.

Works
53,715
Total citations
795,554
Keywords
Plasma MedicineAtmospheric Pressure PlasmasNon-Thermal PlasmaReactive SpeciesBiomedical ApplicationsCold Atmospheric Plasma

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