Pharmacological Effects and Assays
Beta-adrenergic agonists — compounds like clenbuterol, ractopamine, and zilpaterol — are fed to livestock to redirect energy from fat deposition toward lean muscle growth, improving feed efficiency and carcass composition. Their use is tightly regulated or outright banned in many countries because residues in meat can cause cardiovascular and other adverse effects in people who consume it, making reliable detection methods a pressing concern. Researchers are working to understand exactly how these drugs alter muscle fiber structure, tenderness, and water-holding capacity in ways that affect meat quality even when dosing appears compliant. At the same time, efforts continue to develop faster and more sensitive assays — including immunoassay platforms and electrochemical biosensors — capable of identifying trace residue levels across a range of animal species and tissue types.
- Works
- 34,823
- Total citations
- 389,167
- Keywords
- ClenbuterolRactopamineZilpaterolMeat QualityLivestockPerformance
Top papers in Pharmacological Effects and Assays
Ordered by total citation count.
- The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review↗ 3,147
- A STUDY OF THE FACTORS AFFECTING THE ALUMINUM OXIDE-TRIHYDROXYINDOLE PROCEDURE FOR THE ANALYSIS OF CATECHOLAMINES↗ 2,272
- Decreased Catecholamine Sensitivity and β-Adrenergic-Receptor Density in Failing Human Hearts↗ 2,269
- The Respiratory Chain and Oxidative Phosphorylation↗ 2,079
- The Mechanism of Muscular Contraction↗ 1,959
- Genetics of Mouse Behavior: Interactions with Laboratory Environment↗ 1,683
- A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.↗ 1,603OA
- Effect of Inhaled Formoterol and Budesonide on Exacerbations of Asthma↗ 1,519OA
- Age Changes and Sex Differences in Serum Dehydroepiandrosterone Sulfate Concentrations throughout Adulthood↗ 1,362
- GPCR Engineering Yields High-Resolution Structural Insights into β <sub>2</sub> -Adrenergic Receptor Function↗ 1,337
- Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure.↗ 1,320OA
- Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin↗ 1,268
Active researchers
Top authors in this area, ranked by h-index.