Intracranial Aneurysms: Treatment and Complications

An intracranial aneurysm is a focal bulging of a cerebral artery wall that can rupture without warning, flooding the space around the brain with blood in a condition called aneurysmal subarachnoid hemorrhage — an event that kills or permanently disables roughly half of those it strikes. Researchers study how abnormal blood flow patterns and wall shear stress drive aneurysm formation and growth, and how to intervene safely through microsurgical clipping or catheter-based endovascular techniques such as coil embolization and flow diversion. A major unresolved challenge is preventing delayed cerebral ischemia, a secondary injury caused by cerebral vasospasm that can devastate patients who survive the initial bleed. Ongoing work aims to clarify which unruptured aneurysms warrant treatment versus watchful waiting, and to improve the durability of endovascular repairs so that aneurysms do not reopen over time.

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Keywords

Aneurysmal Subarachnoid HemorrhageIntracranial AneurysmsEndovascular TreatmentCerebral VasospasmHemodynamicsNeurosurgical Clipping