Colorectal Cancer Surgical Treatments
Colorectal cancer surgical treatment encompasses the methods used to remove tumors from the colon and rectum, along with the therapies delivered before and after surgery to improve outcomes. A central focus in rectal cancer has been total mesorectal excision—a precise dissection technique that reduces local recurrence—combined with neoadjuvant chemoradiotherapy to shrink tumors before the surgeon operates and adjuvant chemotherapy to eliminate residual microscopic disease afterward. Minimally invasive approaches such as laparoscopic surgery have expanded rapidly, raising ongoing questions about whether they match open surgery in oncological completeness across all tumor stages and locations. Researchers are actively working to identify reliable tumor markers and pathological response measures that could predict which patients will benefit most from aggressive treatment versus those who might safely pursue organ-sparing strategies.
- Works
- 89,640
- Total citations
- 1,315,421
- Keywords
- Preoperative ChemoradiotherapyRectal CancerAdjuvant ChemotherapyLaparoscopic SurgeryTumor MarkersTotal Mesorectal Excision
Top papers in Colorectal Cancer Surgical Treatments
Ordered by total citation count.
- Classification of Surgical Complications↗ 31,161OA
- Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer↗ 11,004OA
- Preoperative versus Postoperative Chemoradiotherapy for Rectal Cancer↗ 6,092
- Signet-Ring Cell Carcinoma of the Colon: A Case Report and Review of the Literature↗ 5,277OA
- Colorectal cancer statistics, 2020↗ 5,150OA
- Colorectal cancer↗ 5,064OA
- Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer↗ 5,056OA
- Preoperative Radiotherapy Combined with Total Mesorectal Excision for Resectable Rectal Cancer↗ 4,226OA
- The Image Biomarker Standardization Initiative: Standardized Quantitative Radiomics for High-Throughput Image-based Phenotyping↗ 3,983OA
- Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer↗ 3,876OA
- Colorectal cancer statistics, 2023↗ 3,849OA
- Leucovorin and Fluorouracil With or Without Oxaliplatin as First-Line Treatment in Advanced Colorectal Cancer↗ 3,823
Active researchers
Top authors in this area, ranked by h-index.