Colorectal Cancer Surgical Treatments
Colorectal cancer surgical treatment encompasses the strategies used to remove tumors of the colon and rectum while minimizing recurrence and preserving patient quality of life, drawing on a combination of operative technique and carefully timed drug and radiation therapies. Central to rectal cancer care is total mesorectal excision, a precise dissection that removes the tumor along with its surrounding lymphatic tissue, often preceded by neoadjuvant chemoradiotherapy to shrink the tumor and improve the odds of a clean surgical margin. Researchers continue to refine how pathological response to preoperative treatment should guide subsequent decisions about adjuvant chemotherapy, and whether patients who achieve a complete response might safely avoid surgery altogether. Minimally invasive approaches such as laparoscopic surgery have also expanded the field's attention toward recovery outcomes and long-term survival equivalence, while tumor markers remain an active area of investigation for predicting prognosis and detecting early recurrence.
- Works
- 88,866
- Total citations
- 1,305,569
- Keywords
- Preoperative ChemoradiotherapyRectal CancerAdjuvant ChemotherapyLaparoscopic SurgeryTumor MarkersTotal Mesorectal Excision
Top papers in Colorectal Cancer Surgical Treatments
Ordered by total citation count.
- Classification of Surgical Complications↗ 30,863OA
- Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer↗ 10,973OA
- Preoperative versus Postoperative Chemoradiotherapy for Rectal Cancer↗ 6,061
- Signet-Ring Cell Carcinoma of the Colon: A Case Report and Review of the Literature↗ 5,277OA
- Colorectal cancer statistics, 2020↗ 5,126OA
- Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer↗ 5,048OA
- Colorectal cancer↗ 4,971OA
- Preoperative Radiotherapy Combined with Total Mesorectal Excision for Resectable Rectal Cancer↗ 4,215OA
- Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer↗ 3,866OA
- The Image Biomarker Standardization Initiative: Standardized Quantitative Radiomics for High-Throughput Image-based Phenotyping↗ 3,862OA
- Leucovorin and Fluorouracil With or Without Oxaliplatin as First-Line Treatment in Advanced Colorectal Cancer↗ 3,818
- Colorectal cancer statistics, 2023↗ 3,793OA
Active researchers
Top authors in this area, ranked by h-index.