Chromosomal and Genetic Variations
Plant genomes are far less stable than they might appear: over evolutionary time, they accumulate duplicated chromosomes, mobile DNA sequences called transposable elements, and wholesale doublings of the entire genome through a process known as polyploidy. Researchers studying these changes want to understand how a genome can absorb such dramatic structural upheaval and still give rise to viable, reproductively isolated species — a question with direct implications for crop improvement and biodiversity. Central open questions include how small RNA molecules and epigenetic signals keep disruptive transposable elements in check after genome duplication, and which features of centromeres — the chromosomal anchors that ensure accurate cell division — allow new species to stabilize rather than collapse under the weight of redundant genetic material.
- Works
- 110,924
- Total citations
- 2,131,281
- Keywords
- Genome EvolutionPolyploidyTransposable ElementsPlant SpeciationSmall RNAsCentromeres
Top papers in Chromosomal and Genetic Variations
Ordered by total citation count.
- MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0↗ 28,848OA
- IQ-TREE: A Fast and Effective Stochastic Algorithm for Estimating Maximum-Likelihood Phylogenies↗ 27,958OA
- RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome↗ 23,745OA
- A Simple, Fast, and Accurate Algorithm to Estimate Large Phylogenies by Maximum Likelihood↗ 17,022OA
- Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype↗ 16,101OA
- GENEPOP (Version 1.2): Population Genetics Software for Exact Tests and Ecumenicism↗ 15,572
- TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions↗ 13,792OA
- DNA polymorphisms amplified by arbitrary primers are useful as genetic markers↗ 13,159OA
- Rapid isolation of high molecular weight plant DNA↗ 12,412OA
- Circos: An information aesthetic for comparative genomics↗ 12,055OA
- Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets↗ 11,993OA
- PCR protocols — A guide to methods and applications↗ 11,779
Active researchers
Top authors in this area, ranked by h-index.