Physical SciencesPhysics and AstronomyRadiation

Advanced Radiotherapy Techniques

Advanced radiotherapy techniques use precisely controlled beams of ionizing radiation to destroy tumor tissue while sparing the healthy structures surrounding it, drawing on physics tools such as Monte Carlo simulation for dose calculation and image guidance to track anatomy in real time. Getting the dose right matters enormously: small errors can leave cancer cells alive or cause serious harm to adjacent organs, so dosimetry and rigorous quality assurance sit at the center of the work. Researchers are actively refining how to account for respiratory motion, which shifts tumors during treatment, and how to optimize dose distributions through intensity modulation so that complex tumor shapes receive lethal exposure without collateral damage. Open questions include how to reduce the long-term risk of radiation-induced secondary cancers and how to make accurate brachytherapy dose calculations routine across the wide variety of implant geometries encountered in clinical practice.

Works
125,192
Total citations
1,207,442
Keywords
Radiotherapy PhysicsDosimetryImage-Guided RadiotherapyIntensity-Modulated RadiotherapyRespiratory Motion ManagementMonte Carlo Simulation

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