Thomas W. Kensler

Top papers

• Cell Survival Responses to Environmental Stresses Via the Keap1-Nrf2-ARE Pathway

  Thomas W. Kensler, Nobunao Wakabayashi, Shyam Biswal·2006·The Annual Review of Pharmacology and Toxicology
  ↗ 3,554
• The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis

  Masayuki Yamamoto, Thomas W. Kensler, Hozumi Motohashi·2018·Physiological Reviews
  ↗ 1,826OA
• Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases

  Antonio Cuadrado, Ana I. Rojo, Geoffrey Wells, et al.·2019·Nature Reviews Drug Discovery
  ↗ 1,341OA
• Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray.

  Rajesh K. Thimmulappa, Kim H., Sorachai Srisuma, et al.·2002·PubMed
  ↗ 1,195
• Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in <i>nrf2</i> transcription factor-deficient mice

  Minerva Ramos‐Gómez, Mi-Kyoung Kwak, Patrick M. Dolan, et al.·2001·Proceedings of the National Academy of Sciences
  ↗ 1,093OA
• Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers

  Nobunao Wakabayashi, Albena T. Dinkova‐Kostova, W. David Holtzclaw, et al.·2004·Proceedings of the National Academy of Sciences
  ↗ 962OA
• Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke–induced emphysema in mice

  Tirumalai Rangasamy, Chung Y. Cho, Rajesh K. Thimmulappa, et al.·2004·Journal of Clinical Investigation
  ↗ 879OA
• Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke–induced emphysema in mice

  Tirumalai Rangasamy, Chung Y. Cho, Rajesh K. Thimmulappa, et al.·2004·Journal of Clinical Investigation
  ↗ 823OA
• Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of<i>Helicobacter pylori</i>and prevents benzo[<i>a</i>]pyrene-induced stomach tumors

  Jed W. Fahey, X. Haristoy, Patrick M. Dolan, et al.·2002·Proceedings of the National Academy of Sciences
  ↗ 791OA
• Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis

  Deepti Malhotra, Élodie Portales-Casamar, Anju Singh, et al.·2010·Nucleic Acids Research
  ↗ 776OA
• Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates.

  Yuesheng Zhang, Thomas W. Kensler, C G Cho, et al.·1994·Proceedings of the National Academy of Sciences
  ↗ 751OA
• The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice

  Junko Wakabayashi, Zhongyan Zhang, Nobunao Wakabayashi, et al.·2009·The Journal of Cell Biology
  ↗ 675OA