Stephan Brand

Top papers

• Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

  Luke Jostins, Stephan Ripke, Rinse K. Weersma, et al.·2012·Nature
  ↗ 4,829OA
• Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

  André Franke, Dermot McGovern, Jeffrey C. Barrett, et al.·2010·Nature Genetics
  ↗ 2,576OA
• CX ₃ CR1-Mediated Dendritic Cell Access to the Intestinal Lumen and Bacterial Clearance

  Jan Hendrik Niess, Stephan Brand, Xiubin Gu, et al.·2005·Science
  ↗ 1,565
• Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

  Carl A. Anderson, Gabrielle Boucher, Charlie W. Lees, et al.·2011·Nature Genetics
  ↗ 1,351OA
• Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

  Isabelle Cleynen, Gabrielle Boucher, Luke Jostins, et al.·2015·The Lancet
  ↗ 766OA
• Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease

  Elaine F. Remmers, Fulya Coşan, Yohei Kirino, et al.·2010·Nature Genetics
  ↗ 671OA
• Crohn’s disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn’s disease

  Stephan Brand·2009·Gut
  ↗ 664
• IL-22 is increased in active Crohn’s disease and promotes proinflammatory gene expression and intestinal epithelial cell migration

  Stephan Brand, Florian Beigel, Torsten Olszak, et al.·2006·American Journal of Physiology-Gastrointestinal and Liver Physiology
  ↗ 542
• Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

  Jimmy Z. Liu, The International PSC Study Group, Johannes R. Hov, et al.·2013·Nature Genetics
  ↗ 395OA
• Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): Upregulated colonic IL-17F expression in active Crohnʼs disease and analysis of the IL17F p.His161Arg polymorphism in IBD

  Julia Seiderer, Ira Elben, Julia Diegelmann, et al.·2007·Inflammatory Bowel Diseases
  ↗ 325OA
• Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment

  Cornelia Tillack, Laura Maximiliane Ehmann, Matthias Friedrich, et al.·2013·Gut
  ↗ 296
• IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes

  Yukihide Momozawa, Julia Dmitrieva, Emilie Théâtre, et al.·2018·Nature Communications
  ↗ 248OA