Philip Cohen

Top papers

• Specificity and mechanism of action of some commonly used protein kinase inhibitors

  Stephen Davies, Helen Reddy, Matilde Caivano, et al.·2000·Biochemical Journal
  ↗ 4,062OA
• The ground state of embryonic stem cell self-renewal

  Qi‐Long Ying, Jason Wray, Jennifer Nichols, et al.·2008·Nature
  ↗ 3,510OA
• PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

  Dario R. Alessi, Ana Cuenda, Philip Cohen, et al.·1995·Journal of Biological Chemistry
  ↗ 3,422OA
• Specificity and mechanism of action of some commonly used protein kinase inhibitors

  Stephen Davies, Helen Reddy, Matilde Caivano, et al.·2000·Biochemical Journal
  ↗ 3,129
• Mechanism of activation of protein kinase B by insulin and IGF-1.

  Dario R. Alessi, Mirjana Andjelković, B. Caudwell, et al.·1996·The EMBO Journal
  ↗ 3,027OA
• THE STRUCTURE AND REGULATION OF PROTEIN PHOSPHATASES

  Philip Cohen·1989·Annual Review of Biochemistry
  ↗ 2,536
• The selectivity of protein kinase inhibitors: a further update

  Jenny Bain, Lorna Plater, Matt Elliott, et al.·2007·Biochemical Journal
  ↗ 2,508OA
• Protein kinases — the major drug targets of the twenty-first century?

  Philip Cohen·2002·Nature Reviews Drug Discovery
  ↗ 2,180
• A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

  John Rouse, Philip Cohen, Sylviane Trigon, et al.·1994·Cell
  ↗ 1,673
• Cyanobacterial microcystin‐LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants

  Carol MacKintosh, Kenneth A. Beattie, Susanne Klumpp, et al.·1990·FEBS Letters
  ↗ 1,651OA
• The renaissance of GSK3

  Philip Cohen, Sheelagh Frame·2001·Nature Reviews Molecular Cell Biology
  ↗ 1,477OA
• The specificities of protein kinase inhibitors: an update

  Jenny Bain, Hilary McLauchlan, Matthew Elliott, et al.·2003·Biochemical Journal
  ↗ 1,357OA