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Author
Patrick M. Sexton
also known as P M Sexton, P SEXTON, P. M. Sexton
Laboratoire de Biologie Physico-Chimique des Protéines Membranaires · University of California, Riverside · University of Essex · Scripps Research Institute
About this author
Works
1,731
Cited by
30,731
h-index
90
i10
338
ORCID ↗
Top papers
Functional Selectivity and Classical Concepts of Quantitative Pharmacology
Jonathan D. Urban, William P. Clarke, Mark von Zastrow, et al.
·
2006
·
Journal of Pharmacology and Experimental Therapeutics
↗ 1,106
Activation and allosteric modulation of a muscarinic acetylcholine receptor
Andrew C. Kruse, Aaron M. Ring, Aashish Manglik, et al.
·
2013
·
Nature
↗ 904
OA
Mechanisms of signalling and biased agonism in G protein-coupled receptors
Denise Wootten, Arthur Christopoulos, Maria Martí-Solano, et al.
·
2018
·
Nature Reviews Molecular Cell Biology
↗ 722
OA
Allosteric Modulation of G Protein–Coupled Receptors
Lauren T. May, Katie Leach, Patrick M. Sexton, et al.
·
2006
·
The Annual Review of Pharmacology and Toxicology
↗ 695
Emerging paradigms in GPCR allostery: implications for drug discovery
Denise Wootten, Arthur Christopoulos, Patrick M. Sexton
·
2013
·
Nature Reviews Drug Discovery
↗ 488
Multiple Amylin Receptors Arise from Receptor Activity-Modifying Protein Interaction with the Calcitonin Receptor Gene Product
George Christopoulos, Katie J. Perry, Maria Morfis, et al.
·
1999
·
Molecular Pharmacology
↗ 480
Phase-plate cryo-EM structure of a class B GPCR–G-protein complex
Yi-Lynn Liang, Maryam Khoshouei, Mazdak Radjainia, et al.
·
2017
·
Nature
↗ 476
OA
Abundant calcitonin receptors in isolated rat osteoclasts. Biochemical and autoradiographic characterization.
Geoffrey C. Nicholson, Jane M. Moseley, Patrick M. Sexton, et al.
·
1986
·
Journal of Clinical Investigation
↗ 458
OA
Muscarinic acetylcholine receptors: novel opportunities for drug development
Andrew C. Kruse, Brian K. Kobilka, Dinesh Gautam, et al.
·
2014
·
Nature Reviews Drug Discovery
↗ 437
OA
Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs
Ron O. Dror, Hillary F. Green, Céline Valant, et al.
·
2013
·
Nature
↗ 425
G-Protein–Coupled Receptor Mas Is a Physiological Antagonist of the Angiotensin II Type 1 Receptor
Evi Kostenis, Graeme Milligan, Arthur Christopoulos, et al.
·
2005
·
Circulation
↗ 411
OA
Glucagon-Like Peptide-1 and Its Class B G Protein–Coupled Receptors: A Long March to Therapeutic Successes
Chris de Graaf, Daniel J Donnelly, Denise Wootten, et al.
·
2016
·
Pharmacological Reviews
↗ 387
OA