John Hardy

Top papers

• The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics

  John Hardy, Dennis J. Selkoe·2002·Science
  ↗ 13,754
• Alzheimer's Disease: The Amyloid Cascade Hypothesis

  John Hardy, Gerald A. Higgins·1992·Science
  ↗ 7,353
• The amyloid hypothesis of Alzheimer's disease at 25 years

  Dennis J. Selkoe, John Hardy·2016·EMBO Molecular Medicine
  ↗ 6,021OA
• Diagnosis and management of dementia with Lewy bodies

  Ian G. McKeith, Dennis W. Dickson, James Lowe, et al.·2005·Neurology
  ↗ 5,048
• Mild cognitive impairment – beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment

  Bengt Winblad, Katie Palmer, Miia Kivipelto, et al.·2004·Journal of Internal Medicine
  ↗ 4,942OA
• Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

  Alison Goate, Marie‐Christine Chartier‐Harlin, Mike Mullan, et al.·1991·Nature
  ↗ 4,636
• Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

  European Alzheimer's Disease Initiative (EADI), Jean‐Charles Lambert, Genetic and Environmental Risk in Alzheimer's Disease (GERAD), et al.·2013·Nature Genetics
  ↗ 4,629OA
• A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD

  Alan E. Renton, Elisa Majounie, Adrian J. Waite, et al.·2011·Neuron
  ↗ 4,441OA
• α-Synuclein Locus Triplication Causes Parkinson's Disease

  A. B. Singleton, Andrew Singleton, Matthew J. Farrer, et al.·2003·Science
  ↗ 4,384
• Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17

  Mike Hutton, Corinne Lendon, Patrizia Rizzu, et al.·1998·Nature
  ↗ 3,505
• Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

  Denise Harold, Richard Abraham, Paul Hollingworth, et al.·2009·Nature Genetics
  ↗ 3,388OA
• <i>TREM2</i> Variants in Alzheimer's Disease

  Rita Guerreiro, Aleksandra Wojtas, José Brás, et al.·2012·New England Journal of Medicine
  ↗ 3,047OA