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Author
John Denis Fryer
also known as Fryer, John, J D Fryer, J Fryer
Translational Genomics Research Institute · Northwestern University · Saint Barnabas Medical Center · Google (United States)
About this author
Works
388
Cited by
14,410
h-index
66
i10
119
ORCID ↗
Top papers
TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics
Ian R. Mackenzie, Alexandra M. Nicholson, Mohona Sarkar, et al.
·
2017
·
Neuron
↗ 644
OA
Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)
Yuka Atagi, Chia‐Chen Liu, Meghan M. Painter, et al.
·
2015
·
Journal of Biological Chemistry
↗ 619
OA
ABCA1 Is Required for Normal Central Nervous System ApoE Levels and for Lipidation of Astrocyte-secreted apoE
Suzanne E. Wahrle, Hong Jiang, Maia Parsadanian, et al.
·
2004
·
Journal of Biological Chemistry
↗ 471
OA
<i>C9ORF72</i> repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits
Jeannie Chew, Tania F. Gendron, Mercedes Prudencio, et al.
·
2015
·
Science
↗ 402
OA
Soluble TREM2 induces inflammatory responses and enhances microglial survival
Li Zhong, Xiao‐Fen Chen, Tingting Wang, et al.
·
2017
·
The Journal of Experimental Medicine
↗ 381
Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis
Yong‐Jie Zhang, Tania F. Gendron, Mark Ebbert, et al.
·
2018
·
Nature Medicine
↗ 335
OA
ATAXIN-1 Interacts with the Repressor Capicua in Its Native Complex to Cause SCA1 Neuropathology
Yung C. Lam, Aaron B. Bowman, Paymaan Jafar‐Nejad, et al.
·
2006
·
Cell
↗ 327
OA
C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins
Yong‐Jie Zhang, Tania F. Gendron, Jonathan C. Grima, et al.
·
2016
·
Nature Neuroscience
↗ 320
Diet and exercise orthogonally alter the gut microbiome and reveal independent associations with anxiety and cognition
Silvia S. Kang, Patricio Jeraldo, Aishe Kurti, et al.
·
2014
·
Molecular Neurodegeneration
↗ 320
OA
TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway
Honghua Zheng, Lin Jia, Chia‐Chen Liu, et al.
·
2017
·
Journal of Neuroscience
↗ 316
OA
Microglial translational profiling reveals a convergent APOE pathway from aging, amyloid, and tau
Silvia S. Kang, Mark Ebbert, Kelsey E. Baker, et al.
·
2018
·
The Journal of Experimental Medicine
↗ 296
OA
Human Apolipoprotein E4 Alters the Amyloid-β 40:42 Ratio and Promotes the Formation of Cerebral Amyloid Angiopathy in an Amyloid Precursor Protein Transgenic Model
John Denis Fryer, Kelly Simmons, Maia Parsadanian, et al.
·
2005
·
Journal of Neuroscience
↗ 286
OA