Joan‐Emma Shea

Top papers

• Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease

  Summer L. Bernstein, Nicholas Dupuis, Noel D. Lazo, et al.·2009·Nature Chemistry
  ↗ 911OA
• Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer’s Disease, Parkinson’s Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis

  Phuong H. Nguyen, Ayyalusamy Ramamoorthy, Bikash R. Sahoo, et al.·2021·Chemical Reviews
  ↗ 652OA
• Moltemplate: A Tool for Coarse-Grained Modeling of Complex Biological Matter and Soft Condensed Matter Physics

  Andrew I. Jewett, David Stelter, Jason Lambert, et al.·2021·Journal of Molecular Biology
  ↗ 495OA
• F<scp>ROM</scp>F<scp>OLDING</scp>T<scp>HEORIES TO</scp>F<scp>OLDING</scp>P<scp>ROTEINS</scp>: A Review and Assessment of Simulation Studies of Protein Folding and Unfolding

  Joan–Emma Shea, Charles L. Brooks·2001·Annual Review of Physical Chemistry
  ↗ 480
• Amyloid β-Protein:  Monomer Structure and Early Aggregation States of Aβ42 and Its Pro¹⁹Alloform

  Summer L. Bernstein, Thomas Wyttenbach, Andrij Baumketner, et al.·2005·Journal of the American Chemical Society
  ↗ 339
• Complete Phase Diagram for Liquid–Liquid Phase Separation of Intrinsically Disordered Proteins

  James McCarty, Kris T. Delaney, Scott P. O. Danielsen, et al.·2019·The Journal of Physical Chemistry Letters
  ↗ 295OA
• Amyloid β‐protein monomer structure: A computational and experimental study

  Andrij Baumketner, Summer L. Bernstein, Thomas Wyttenbach, et al.·2006·Protein Science
  ↗ 246OA
• Exploring the origins of topological frustration: Design of a minimally frustrated model of fragment B of protein A

  Joan–Emma Shea, José N. Onuchic, Charles L. Brooks·1999·Proceedings of the National Academy of Sciences
  ↗ 240OA
• Role of Water in Mediating the Assembly of Alzheimer Amyloid-β Aβ16−22 Protofilaments

  Mary Griffin Krone, Lan Hua, Patricia Soto, et al.·2008·Journal of the American Chemical Society
  ↗ 224
• The Amyloid Formation Mechanism in Human IAPP: Dimers Have β-Strand Monomer−Monomer Interfaces

  Nicholas Dupuis, Chun Wu, Joan–Emma Shea, et al.·2011·Journal of the American Chemical Society
  ↗ 213
• Human Islet Amyloid Polypeptide Monomers Form Ordered β-hairpins: A Possible Direct Amyloidogenic Precursor

  Nicholas Dupuis, Chun Wu, Joan–Emma Shea, et al.·2009·Journal of the American Chemical Society
  ↗ 211
• Elucidating Amyloid β-Protein Folding and Assembly:  A Multidisciplinary Approach

  David B. Teplow, Noel D. Lazo, Gal Bitan, et al.·2006·Accounts of Chemical Research
  ↗ 206OA