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Author
Gordon J. Freeman
also known as Freeman, G, Freeman, G.J., Freeman, Gordon J.
Harvard University · Dana-Farber Cancer Institute · Broad Institute · Boston University
About this author
Works
1,085
Cited by
130,829
h-index
175
i10
422
ORCID ↗
Top papers
Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response
Peng Jiang, Shengqing Gu, Deng Pan, et al.
·
2018
·
Nature Medicine
↗ 5,485
OA
PD-1 and Its Ligands in Tolerance and Immunity
Mary Keir, Manish J. Butte, Gordon J. Freeman, et al.
·
2008
·
Annual Review of Immunology
↗ 5,300
OA
Restoring function in exhausted CD8 T cells during chronic viral infection
Daniel L. Barber, E. John Wherry, David Masopust, et al.
·
2005
·
Nature
↗ 3,943
PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma
Stephen M. Ansell, Alexander M. Lesokhin, Ivan Borrello, et al.
·
2014
·
New England Journal of Medicine
↗ 3,529
OA
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
Cheryl L. Day, Daniel E. Kaufmann, Photini Kiepiela, et al.
·
2006
·
Nature
↗ 2,637
THE B7 FAMILY REVISITED
Rebecca J. Greenwald, Gordon J. Freeman, Arlene H. Sharpe
·
2005
·
Annual Review of Immunology
↗ 2,281
CTLA-4 can function as a negative regulator of T cell activation
Theresa L. Walunas, Deborah J. Lenschow, Christina Y. Bakker, et al.
·
1994
·
Immunity
↗ 2,193
Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
Shawn D. Blackburn, Haina Shin, W. Nicholas Haining, et al.
·
2008
·
Nature Immunology
↗ 2,044
OA
Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy
Se Jin Im, Masao Hashimoto, Michael Y. Gerner, et al.
·
2016
·
Nature
↗ 2,033
OA
PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
Loise M. Francisco, Victor H. Salinas, Keturah Brown, et al.
·
2009
·
The Journal of Experimental Medicine
↗ 2,030
OA
Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
Matthew M. Gubin, Xiuli Zhang, Heiko Schuster, et al.
·
2014
·
Nature
↗ 1,975
OA
CD4+CD25high Regulatory Cells in Human Peripheral Blood
Clare Baecher‐Allan, Julia A. Brown, Gordon J. Freeman, et al.
·
2001
·
The Journal of Immunology
↗ 1,846
OA