Frederick W. Alt

Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

An early haematopoietic defect in mice lacking the transcription factor GATA-2

SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation

Plasma cell differentiation requires the transcription factor XBP-1

Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC‐1α

Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation

SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage.

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice