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Author
Frédéric J. de Sauvage
also known as F De Sauvage, F J de Sauvage, F. DE SAUVAGE
Molecular Oncology (United States) · Novartis (Switzerland) · American Academy of Ophthalmology · Howard Hughes Medical Institute
About this author
Works
306
Cited by
49,327
h-index
104
i10
173
ORCID ↗
Top papers
Influence of tumour micro-environment heterogeneity on therapeutic response
Melissa R. Junttila, Frédéric J. de Sauvage
·
2013
·
Nature
↗ 2,615
Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
Yan Zheng, Patricia Valdez, Dimitry M. Danilenko, et al.
·
2008
·
Nature Medicine
↗ 1,888
Interleukin-23 Promotes a Distinct CD4 T Cell Activation State Characterized by the Production of Interleukin-17
Sudeepta Aggarwal, Nico Ghilardi, Ming-Hong Xie, et al.
·
2003
·
Journal of Biological Chemistry
↗ 1,836
OA
Activating Smoothened mutations in sporadic basal-cell carcinoma
Jingwu Xie, Maximilien Murone, Shiuh-Ming Luoh, et al.
·
1998
·
Nature
↗ 1,337
Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand
Frédéric J. de Sauvage, Philip E. Hass, Susan D. Spencer, et al.
·
1994
·
Nature
↗ 1,310
A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable
Hua Tian, Brian Biehs, Søren Warming, et al.
·
2011
·
Nature
↗ 1,193
OA
Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma
Daniel D. Von Hoff, Patricia LoRusso, Charles M. Rudin, et al.
·
2009
·
New England Journal of Medicine
↗ 1,110
OA
The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog
Donna M. Stone, Mary Hynes, Mark Armanini, et al.
·
1996
·
Nature
↗ 1,110
Characterization of a multicomponent receptor for GDNF
James Treanor, Laurie J. Goodman, Frédéric J. de Sauvage, et al.
·
1996
·
Nature
↗ 1,095
Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
Charles M. Rudin, Steffen Durinck, Eric Stawiski, et al.
·
2012
·
Nature Genetics
↗ 1,093
Diverse somatic mutation patterns and pathway alterations in human cancers
Zhengyan Kan, Bijay S. Jaiswal, Jeremy Stinson, et al.
·
2010
·
Nature
↗ 1,026
Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449
Charles M. Rudin, Christine L. Hann, John Laterra, et al.
·
2009
·
New England Journal of Medicine
↗ 1,012
OA