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Author
Ernesto Freire
also known as E FREIRE, E Freire, E. Freire
Johns Hopkins University · Johns Hopkins Medicine · University of Baltimore · Rutgers, The State University of New Jersey
About this author
Works
295
Cited by
24,069
h-index
89
i10
233
ORCID ↗
Top papers
HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites
Peter D. Kwong, Michael L. Doyle, David J. Casper, et al.
·
2002
·
Nature
↗ 895
Direct measurement of protein binding energetics by isothermal titration calorimetry
Stephanie A. Leavitt, Ernesto Freire
·
2001
·
Current Opinion in Structural Biology
↗ 684
Isothermal titration calorimetry
Ernesto Freire, Obdulio López Mayorga, Martin Straume
·
1990
·
Analytical Chemistry
↗ 590
Thermodynamics of Structural Stability and Cooperative Folding Behavior in Proteins
Kenneth P. Murphy, Ernesto Freire
·
1992
·
Advances in protein chemistry
↗ 573
OA
Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus <i>ex Vivo</i> and Distribution <i>in Vivo</i>
Qingguo Xu, Laura M. Ensign, Nicholas J. Boylan, et al.
·
2015
·
ACS Nano
↗ 550
Do enthalpy and entropy distinguish first in class from best in class?
Ernesto Freire
·
2008
·
Drug Discovery Today
↗ 480
OA
The heat capacity of proteins
Javier Gómez, Vincent J. Hilser, Dong Xie, et al.
·
1995
·
Proteins Structure Function and Bioinformatics
↗ 434
Adding calorimetric data to decision making in lead discovery: a hot tip
John E. Ladbury, G. Klebe, Ernesto Freire
·
2009
·
Nature Reviews Drug Discovery
↗ 395
Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
Young Do Kwon, Marie Pancera, Priyamvada Acharya, et al.
·
2015
·
Nature Structural & Molecular Biology
↗ 367
OA
Statistical mechanical deconvolution of thermal transitions in macromolecules. I. Theory and application to homogeneous systems
Ernesto Freire, Rodney L. Biltonen
·
1978
·
Biopolymers
↗ 353
Isothermal titration calorimetry to determine association constants for high-affinity ligands
Adrián Velázquez‐Campoy, Ernesto Freire
·
2006
·
Nature Protocols
↗ 330
A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite
Neville K. Kisalu, Azza H. Idris, Connor Weidle, et al.
·
2018
·
Nature Medicine
↗ 310
OA